Pathology Playground: Crowd Unknowns
Below are pathology unknowns cases in which you can order immunostains and molecular studies. Choose your case, and when presented with a text box, begin typing the immuno or other study you'd like, and select it from the Autocomplete list. Enter your diagnosis to see if you're correct and see a presentation. If you want to upload your own cases, Login at the top right and go to the Dashboard. Watch a Youtube video on how to use the site and upload your own cases here.
Abnormal lab test
A 21-year-old female with no previous medical history was admitted with acute abdomen. Coagulation screening tests were ordered for impending urgent surgery for acute appendicitis.
Frequent bruising and hematoma
A 5 year-old girl (adopted) brought by her mother with frequent bruising and severe periorbital hematoma after laceration of left eyebrow. Mother tells the clinician that her daughter cut her left eyebrow with scissors 2 weeks ago. For 2-4 days, it looked as it was healing well and then it looked like fresh bleeding at the injury site. This cycle of healing and worsening repeated but the wound still does not seem healing.
Bruising after playing soccer
7-year-old boy with complains of multiple bruises on his legs and arms. Recently he started to play football with his friends and his mother noticed the bruises. After questioning mother, she remembers his son had nosebleeds a few times in the past, mainly at wintertime. It usually stopped after a short time and thought it was due to the dry air in the house. No medical care was needed. Boy is healthy, rarely has cold symptoms, and not on any medication.
Severe menorrhagia
A 14-year-old girl came to the pediatrician with complains menstrual period lasting for 6-7 days. She needs to get up 1-2 times during the night to change her pads. She stopped her basketball practice when she has her period because she soaks through her pads during practice. She is not receiving any medication.
Severe bleeding after delivery
30-year-old woman with recent delivery of her second baby 4 months ago, presents with large hematoma on her thigh. She does not recall any injury to the site. No significant history of bleeding or medication. Blood was drawn from left forearm.
Uncontrolled bleeding in a newborn
2 weeks old male neonate presented with uncontrolled bleeding at circumcision site. Initial work up studies are shown.