Pathology Playground: Crowd Unknowns
Below are pathology unknowns cases in which you can order immunostains and molecular studies. Choose your case, and when presented with a text box, begin typing the immuno or other study you'd like, and select it from the Autocomplete list. Enter your diagnosis to see if you're correct and see a presentation. If you want to upload your own cases, Login at the top right and go to the Dashboard. Watch a Youtube video on how to use the site and upload your own cases here.
Brain mass
77 yo M, ICH and mass, could be primary or met per radiology. No systemic disease (careful with the name, use WHO considering the location)
Cerebral vein thrombosis in a young female patient
A female patient in her fourth decade presented with several months right sided headache associated with nausea. CT head showed extensive cerebral venous thrombosis. Patient was taking OCP at the time which was thought to be the provoking event. OCPs discontinued, patient was placed on anticoagulation.
Abnormal lab test
A 21-year-old female with no previous medical history was admitted with acute abdomen. Coagulation screening tests were ordered for impending urgent surgery for acute appendicitis.
Frequent bruising and hematoma
A 5 year-old girl (adopted) brought by her mother with frequent bruising and severe periorbital hematoma after laceration of left eyebrow. Mother tells the clinician that her daughter cut her left eyebrow with scissors 2 weeks ago. For 2-4 days, it looked as it was healing well and then it looked like fresh bleeding at the injury site. This cycle of healing and worsening repeated but the wound still does not seem healing.
Bruising after playing soccer
7-year-old boy with complains of multiple bruises on his legs and arms. Recently he started to play football with his friends and his mother noticed the bruises. After questioning mother, she remembers his son had nosebleeds a few times in the past, mainly at wintertime. It usually stopped after a short time and thought it was due to the dry air in the house. No medical care was needed. Boy is healthy, rarely has cold symptoms, and not on any medication.
Severe menorrhagia
A 14-year-old girl came to the pediatrician with complains menstrual period lasting for 6-7 days. She needs to get up 1-2 times during the night to change her pads. She stopped her basketball practice when she has her period because she soaks through her pads during practice. She is not receiving any medication.
Left arm deep vein thrombosis
A 27-year-old man presented with swelling in the left arm. Doppler ultrasound showed deep vein thrombosis. He has no history of recent travel, immobility, excessive bleeding or medication. Initial laboratory findings are shown.