Specimen: Head of pancreas Body of pancreas Tail of pancreas Duodenum Stomach Common bile duct Gallbladder Spleen Adjacent large vessels: Portal vein Superior mesenteric vein Other large vessel (specify): Other (specify): Not specified Cannot be determined Procedure: Pancreaticoduodenectomy (Whipple resection), partial pancreatectomy Pancreaticoduodenectomy (Whipple resection), total pancreatectomy Partial pancreatectomy, pancreatic body Partial pancreatectomy, pancreatic tail Other (specify): Not specified Tumor Site: Pancreatic head Uncinate process Pancreatic body Pancreatic tail Other (specify): Cannot be determined Not specified Tumor Size: Greatest dimension (cm): Additional dimensions (cm): Cannot be determined (see Comment) Histologic Type: Ductal adenocarcinoma Mucinous noncystic carcinoma Signet-ring cell carcinoma Adenosquamous carcinoma Undifferentiated (anaplastic) carcinoma Undifferentiated carcinoma with osteoclast-like giant cells Mixed ductal-endocrine carcinoma Serous cystadenocarcinoma Mucinous cystic neoplasm Noninvasive Invasive Intraductal papillary-mucinous carcinoma Noninvasive Invasive Acinar cell carcinoma Acinar cell cystadenocarcinoma Mixed acinar-endocrine carcinoma Other (specify): Histologic Grade (ductal carcinoma only): Not applicable GX: Cannot be assessed G1: Well differentiated G2: Moderately differentiated G3: Poorly differentiated G4: Undifferentiated Other (specify): Microscopic Tumor Extension: Cannot be assessed No evidence of primary tumor Carcinoma in situ Tumor is confined to pancreas Tumor invades ampulla of Vater or sphincter of Oddi Tumor invades duodenal wall Tumor invades peripancreatic soft tissues: Tumor invades retroperitoneal soft tissue Tumor invades mesenteric adipose tissue Tumor invades mesocolon Tumor invades other peripancreatic soft tissue: Tumor invades extrapancreatic common bile duct Tumor invades other adjacent organs or structures: Margins: Cannot be assessed Margins uninvolved by invasive carcinoma, distance of invasive carcinoma from closest margin: mm at Margins uninvolved by carcinoma in situ Margin(s) involved by carcinoma in situ: Carcinoma in situ present at common bile duct margin Carcinoma in situ present at pancreatic parenchymal margin Margin(s) involved by invasive carcinoma: Uncinate process (retroperitoneal) margin (nonperitonealized surface of the uncinate process) Distal pancreatic margin Common bile duct margin Proximal pancreatic margin Other (specify): Invasive carcinoma involves posterior retroperitoneal surface of pancreas Treatment Effect: No prior treatment Present: No residual tumor (complete response, grade 0) Marked response (grade 1, minimal residual cancer) Moderate response (grade 2) No definite response identified (grade 3, poor or no response) Not known Lymph-Vascular Invasion: Not identified Present Indeterminate Perineural Invasion: Not identified Present Indeterminate Pathologic Staging (pTNM) m (multiple primary tumors) r (recurrent) y (post-treatment) Primary Tumor (pT): pTX: Cannot be assessed pT0: No evidence of primary tumor pTis: Carcinoma in situ pT1: Tumor limited to the pancreas, 2 cm or less in greatest dimension pT2: Tumor limited to the pancreas, more than 2 cm in greatest dimension pT3: Tumor extends beyond the pancreas but without involvement of the celiac axis or the superior mesenteric artery pT4: Tumor involves the celiac axis or the superior mesenteric artery Regional Lymph Nodes (pN): pNX: Cannot be assessed pN0: No regional lymph node metastasis ( 0 / ) pN1: Regional lymph node metastasis ( / ) No nodes submitted or found Distant Metastasis (pM): Not applicable pM1: Distant metastasis at Additional Pathologic Findings: None identified Pancreatic intraepithelial neoplasia (highest grade: PanIN ) Chronic pancreatitis Acute pancreatitis Other (specify): Ancillary Studies: Clinical History: Neoadjuvant therapy Familial pancreatitis Familial pancreatic cancer syndrome Other (specify): Not specified Comment(s):