NASAL CAVITY AND PARANASAL SINUSES: Incisional Biopsy, Excisional Biopsy, Resection

Specimen:
   Nasal cavity:
    Septum
    Floor
    Lateral wall
    Vestibule
   Paranasal sinus(es), maxillary
   Paranasal sinus(es), ethmoid
   Paranasal sinus(es), frontal
   Paranasal sinus(es), sphenoid
   Other (specify):
   Not specified

Received:
Fresh
In formalin
Other (specify):

Procedure Type:
   Incisional Biopsy
   Excisional Biopsy
   Resection:
    Partial maxillectomy
    Radical maxillectomy
   Neck (lymph node) Dissection (specify):
   Other (specify):
   Not Specified

Specimen Integrity:
    Intact
    Fragmented

Specimen Size:
Greatest dimensions (cm):
Additional dimensions (if more than one part) (cm):

Specimen Laterality:
   Right
   Left
   Bilateral
   Midline
   Not specified

Tumor Site:
   Nasal cavity:
    Septum
    Floor
    Lateral wall
    Vestibule
   Paranasal sinus(es), maxillary
   Paranasal sinus(es), ethmoid
   Paranasal sinus(es), frontal
   Paranasal sinus(es), sphenoid
   Other (specify):
   Not specified

Tumor Focality:
   Single focus
   Bilateral
   Multifocal (specify):

Tumor Size:
Greatest dimension (cm):
Additional dimensions (cm):
Cannot be determined:

Tumor Description: Gross subtype:
    Polypoid
    Exophytic
    Endophytic
    Ulcerated
    Sessile
    Other (specify):

Macroscopic Extent of Tumor:

Histologic Type:
   Carcinomas of the Nasal Cavity and Paranasal Sinuses:
       Squamous cell carcinoma, conventional:
        Keratinizing
        Nonkeratinizing (formerly cylindrical cell, transitional cell)
   Variants of Squamous Cell Carcinoma:
       Acantholytic squamous cell carcinoma
       Adenosquamous carcinoma
       Basaloid squamous cell carcinoma
       Papillary squamous cell carcinoma
       Spindle cell squamous cell carcinoma
       Verrucous carcinoma
   Giant cell carcinoma
   Lymphoepithelial carcinoma (non-nasopharyngeal)
   Sinonasal undifferentiated carcinoma (SNUC)
   Adenocarcinoma, Non-Salivary Gland Type:
       Intestinal type:
        Papillary-type
        Colonic-type
        Solid type
        Mucinous type
        Mixed type
       Non-intestinal type:
        Low grade
        Intermediate grade
        High grade
   Carcinomas of Minor Salivary Glands:
       Acinic cell carcinoma
       Adenoid cystic carcinoma
       Adenocarcinoma, not otherwise specified (NOS):
        Low grade
        Intermediate grade
        High grade
       Carcinoma ex pleomorphic adenoma (malignant mixed tumor)
       Clear cell adenocarcinoma
       Epithelial-myoepithelial carcinoma
       Mucoepidermoid carcinoma:
        Low grade
        Intermediate grade
        High grade
       Myoepithelial carcinoma (malignant myoepithelioma)
       Oncocytic carcinoma
       Polymorphous low-grade adenocarcinoma
       Salivary duct carcinoma
       Other (specify):
   Neuroendocrine Carcinoma:
       Typical carcinoid tumor (well differentiated neuroendocrine carcinoma)
       Atypical carcinoid tumor (moderately differentiated neuroendocrine carcinoma)
       Small cell carcinoma (poorly differentiated neuroendocrine carcinoma)
       Combined (or composite) small cell carcinoma, neuroendocrine type
   Mucosal malignant melanoma
   Other (specify):
   Carcinoma, type cannot be determined

Histologic Grade:
Not applicable
GX: Cannot be assessed
G1: Well differentiated
G2: Moderately differentiated
G3: Poorly differentiated
Other (specify):

Microscopic Tumor Extension:

Margins:
   Cannot be assessed
   Margins uninvolved by invasive carcinoma, distance from closest margin: at
   Margins involved by invasive carcinoma at
   Margins uninvolved by carcinoma in situ (includes moderate and severe dysplasia), distance from closest margin: at
   Margins involved by carcinoma in situ (includes moderate and severe dysplasia) at
   Not applicable

Treatment Effect (applicable to carcinomas treated with neoadjuvant therapy):
    Not identified
    Present (specify):
    Indeterminate

Lymph-Vascular Invasion:
Not Identified
Present
Indeterminate

Perineural Invasion:
Not identified
Present
Indeterminate

Lymph Nodes, Extranodal Extension:
Not identified
Present
Indeterminate

Pathologic Staging (pTNM):
TNM Descriptors

m (multiple primary tumors)
r (recurrent)
y ( post-treatment)

Primary Tumor (pT):
    pTX: Cannot be assessed
    pT0: No evidence of primary tumor
    pTis: Carcinoma in situ
Primary Tumor (pT): Maxillary Sinus:
    pT1: Tumor limited to maxillary sinus mucosa with no erosion or destruction of bone
    pT2: Tumor causing bone erosion or destruction including extension into the hard palate and/or middle nasal meatus, except extension to posterior wall of maxillary sinus and pterygoid plates
    pT3: Tumor invades any of the following: bone of the posterior wall of maxillary sinus, subcutaneous tissues, floor or medial wall of orbit, pterygoid fossa, ethmoid sinuses
    pT4a: Moderately advanced local disease. Tumor invades anterior orbital contents, skin of cheek, pterygoid plates, infratemporal fossa, cribriform plate, sphenoid or frontal sinuses
    pT4b: Very advanced local disease. Tumor invades any of the following: orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary division of trigeminal nerve (V2), nasopharynx, or clivus
Primary Tumor (pT): Nasal Cavity and Ethmoid Sinus:
    pT1: Tumor restricted to any one subsite, with our without bone invasion
    pT2: Tumor invading two subsites in a single region or extending to involve an adjacent region within the nasoethmoidal complex, with our without bone invasion
    pT3: Tumor extends to invade the medial wall or floor of the orbit, maxillary sinus, palate, or cribriform plate
    pT4a: Moderately advanced local disease Tumor invades any of the following: anterior orbital contents, skin of nose or cheek, minimal extension to anterior cranial fossa, pterygoid plates, sphenoid or frontal sinuses
    pT4b: Very advanced local disease. Tumor invades any of the following: orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary division of trigeminal nerve (V2), nasopharynx, or clivus
Primary Tumor (pT):Mucosal Malignant Melanoma

    pT3: Mucosal disease
    pT4a: Moderately advanced disease. Tumor involving deep soft tissue, cartilage, bone, or overlying skin
    pT4b: Very advanced disease. Tumor involving brain, dura, skull base, lower cranial nerves (IX, X, XI, XII), masticator space, carotid artery, prevertebral space, or mediastinal structures

Regional Lymph Nodes (pN):
Non-Mucosal Malignant Melanoma
pNX: Cannot be assessed
pN0: No regional lymph node metastasis ( 0 / )
pN1: Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension ( 1 / )
pN2: Metastasis in a single ipsilateral lymph node, more than 3cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral nodes, none more than 6 cm in greatest dimension ( 1 / )
pN2a: Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension ( 1 / )
pN2b: Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension ( / )
pN2c: Metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension ( / )
pN3: Metastasis in a lymph node more than 6 cm in greatest dimension ( / )
Mucosal Malignant Melanoma:
pNX: Regional lymph nodes cannot be assessed
pN0: No regional lymph node metastases ( 0 / )
pN1: Regional lymph node metastases present ( / )

Metastases at level VII are considered regional lymph node metastases. Midline nodes are considered ipsilateral nodes.

Size of the largest positive lymph node (cm):
Size of the associated metastatic focus (mm):
Position of the involved node (level):

Distant Metastasis (pM):
Not applicable
pM1: Distant metastasis at Specify site(s) if known and source of pathologic metastatic specimen

Additional Pathologic Findings:
   None identified
   Carcinoma in situ
   Epithelial dysplasia:
   Inflammation (specify type):
   Squamous metaplasia
   Epithelial hyperplasia
   Colonization:
    Fungal
    Bacterial
   Other (specify):

Ancillary Studies:

Treatment History:
       Neoadjuvant therapy:
        Yes (specify type):
        No
        Indeterminate
       Other (specify):

Comment(s):