HEPATOCELLULAR CARCINOMA: Hepatic Resection

Specimen:
   Liver
   Gallbladder
   Other (specify):
   Not specified

Procedure Type:
   Wedge resection
   Partial hepatectomy
   Major hepatectomy (3 segments or more)
   Minor hepatectomy (less than 3 segments)
   Total hepatectomy
   Other (specify):
   Not specified

Tumor Size:
   Greatest dimension (cm):
   Additional dimensions (cm):
   Cannot be determined (see Comment)

Tumor Focality:
Solitary (specify location):
Multiple (specify location):

Histologic Type:
Hepatocellular carcinoma
Fibrolamellar hepatocellular carcinoma
Undifferentiated carcinoma
Other (specify):
Carcinoma, type cannot be determined

Histologic Grade:
Not applicable
GX: Cannot be assessed
GI: Well differentiated
GII: Moderately differentiated
GIII: Poorly differentiated
GIV: Undifferentiated/anaplastic
Other (specify):

Tumor Extension:
   Tumor confined to liver
   Tumor involves a major branch of the portal vein
   Tumor involves 1 or more hepatic vein(s)
   Tumor involves visceral peritoneum
   Tumor directly invades gallbladder
   Tumor directly invades other adjacent organs (specify):

Margins:
   Parenchymal Margin:
    Cannot be assessed
    Uninvolved by invasive carcinoma, Distance of invasive carcinoma from closest margin: mm at
    Involved by invasive carcinoma
   Other:
    Cannot be assessed
    Uninvolved by invasive carcinoma
    Involved by invasive carcinoma

Lymph-Vascular Invasion:
Macroscopic Venous (Large Vessel) Invasion (V):
Not identified
Present
Indeterminate

Microscopic (Small Vessel) Invasion (L):
Not identified
Present
Indeterminate

Perineural Invasion:
Not identified
Present
Indeterminate

Pathologic Staging (pTNM)

TNM Descriptors (select all that apply)
m (multiple primary tumors)
r (recurrent)
y (post-treatment)

Primary Tumor (pT):
pTX: Cannot be assessed
pT0: No evidence of primary tumor
pT1: Solitary tumor without vascular invasion
pT2: Solitary tumor with vascular invasion or multiple tumors none more than 5 cm
pT3a: Multiple tumors more than 5 cm
pT3b: Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic veins
pT4: Tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum

Regional Lymph Nodes (pN):
pNX: Cannot be assessed
pN0: No regional lymph node metastasis ( 0 / )
pN1: Regional lymph node metastasis ( / )

Distant Metastasis (pM):
Not applicable
pM1: Distant metastasis at

Additional Pathologic Findings:
   Fibrosis score:
    Cirrhosis/severe fibrosis (Ishak score 5-6) (F1)
    None to moderate fibrosis (Ishak score 0-4) (F2)
   Hepatocellular dysplasia
   Low-grade dysplastic nodule
   High-grade dysplastic nodule
   Steatosis
   Iron overload
   Chronic hepatitis (specify etiology):
   Other (specify):
   None identified

Ancillary Studies:

Disease History:
   Cirrhosis
   Hepatitis C infection
   Hepatitis B infection
   Alcoholic liver disease
   Obesity
   Hereditary hemochromatosis
   Other (specify):
   Not known

Comments: