Specimen: Liver Gallbladder Other (specify): Not specified Procedure: Wedge resection Partial hepatectomy Major hepatectomy (3 segments or more) Minor hepatectomy (less than 3 segments) Total hepatectomy Other (specify): Not specified Tumor Size: Greatest dimension: cm Additional dimensions: cm Cannot be determined (see Comment) Tumor Focality: Solitary (specify location): Multiple (specify locations): Histologic Type: Cholangiocarcinoma Combined hepatocellular and cholangiocarcinoma Bile duct cystadenocarcinoma Other (specify): Histologic Grade: Not applicable GX: Cannot be assessed GI: Well differentiated GII: Moderately differentiated GIII: Poorly differentiated GIV: Undifferentiated Other (specify): Tumor Growth Pattern: Mass-forming Periductal infiltrating Mixed mass-forming and periductal infiltrating Cannot be determined Microscopic Tumor Extension: Cannot be assessed No evidence of primary tumor Tumor confined to the intrahepatic bile ducts histologically (carcinoma in situ) Tumor confined to hepatic parenchyma Tumor involves visceral peritoneal surface Tumor directly invades gallbladder Tumor directly invades adjacent organs other than the gallbladder (specify): Margins: Hepatic Parenchymal Margin: Cannot be assessed Uninvolved by invasive carcinoma, distance of invasive carcinoma from closest margin: mm at Involved by invasive carcinoma Bile Duct Margin: Cannot be assessed Uninvolved by invasive carcinoma: Dysplasia/carcinoma in situ not identified Dysplasia/carcinoma in situ present Involved by invasive carcinoma Other Margin Margin: Cannot be assessed Uninvolved by invasive carcinoma Involved by invasive carcinoma Lymph-Vascular Invasion Venous (Major Vessel) Invasion (V) (invasion of right or left portal vein, 1 or more hepatic veins): Not identified Present Indeterminate Small Vessel Invasion (L): Not identified Present Indeterminate Perineural Invasion: Not identified Present Indeterminate Pathologic Staging (pTNM) m (multiple primary tumors) r (recurrent) y (posttreatment) Primary Tumor (pT): pTX: Cannot be assessed pT0: No evidence of primary tumor pTis: Carcinoma in situ (intraductal tumor) pT1: Solitary tumor without vascular invasion pT2a: Solitary tumor with vascular invasion pT2b: Multiple tumors, with or without vascular invasion pT3: Tumor perforating the visceral peritoneum or involving the local extrahepatic structures by direct invasion pT4: Tumor with periductal invasion Regional Lymph Nodes (pN): pNX: Cannot be assessed pN0: No regional lymph node metastasis ( 0 / ) pN1: Regional lymph node metastasis ( / ) No nodes submitted or found Distant Metastasis (pM): Not applicable pM1: Distant metastasis ( ) Additional Pathologic Findings: Cirrhosis/severe fibrosis (Ishak fibrosis score 5-6) Primary sclerosing cholangitis Biliary stones Chronic hepatitis (specify type): Other (specify): None identified Ancillary Studies: Clinical History: Cirrhosis Primary sclerosing cholangitis Inflammatory bowel disease Hepatitis C infection Other (specify): Not known Comments: