Specimen: Esophagus Proximal stomach Other (specify): Not specified Procedure: Endoscopic resection Esophagectomy Esophagogastrectomy Other (specify): Not specified Tumor Site: Cervical (proximal) esophagus Midesophagus: Upper thoracic esophagus Midthoracic esophagus Distal esophagus (lower thoracic esophagus) Esophagogastric junction (EGJ) Proximal stomach and esophagogastric junction Other (specify): Not specified Relationship of Tumor to Esophagogastric Junction: Tumor is entirely located within the tubular esophagus and does not involve the esophagogastric junction Tumor midpoint lies in the distal esophagus and tumor involves the esophagogastric junction Tumor midpoint is located at the esophagogastric junction Tumor midpoint lies in the proximal stomach or cardia and tumor involves the esophagogastric junction Not specified Cannot be assessed Distance of tumor center from esophagogastric junction (specify, if applicable): cm Tumor Size: Greatest dimension (cm): Additional dimensions (cm): Cannot be determined (see Comment) Histologic Type: Squamous cell carcinoma Adenocarcinoma Adenosquamous carcinoma Small cell carcinoma Undifferentiated carcinoma Other (specify): Carcinoma, type cannot be determined Histologic Grade: Not applicable GX: Cannot be assessed G1: Well differentiated G2: Moderately differentiated G3: Poorly differentiated G4: Undifferentiated Microscopic Tumor Extension: Cannot be assessed No evidence of primary tumor High-grade dysplasia (carcinoma in situ) Tumor invades lamina propria Tumor invades muscularis mucosae Tumor invades submucosa Tumor invades muscularis propria Tumor invades through the muscularis propria into the periesophageal soft tissue (adventitia) Tumor directly invades adjacent structures: Margins: Proximal Margin: Cannot be assessed Uninvolved by invasive carcinoma Involved by invasive carcinoma Uninvolved by dysplasia Involved by dysplasia: Squamous dysplasia Intestinal metaplasia (Barrett’s esophagus) with dysplasia Involved by intestinal metaplasia (Barrett’s esophagus) without dysplasia Distal Margin: Cannot be assessed Uninvolved by invasive carcinoma or dysplasia Involved by invasive carcinoma Involved by dysplasia: Squamous dysplasia Intestinal metaplasia (Barrett’s esophagus) with dysplasia Involved by intestinal metaplasia (Barrett’s esophagus) without dysplasia Circumferential (Adventitial) Margin (esophagectomy or esophagogastrectomy specimens) or Deep Margin (endoscopic resection specimens): Cannot be assessed Uninvolved by invasive carcinoma Involved by invasive carcinoma Distance of invasive carcinoma from closest margin: cm at Treatment Effect: No prior treatment Present: No residual tumor (complete response, grade 0) Marked response (grade 1, minimal residual cancer) Moderate response (grade 2) No definite response identified (grade 3, poor or no response) Treatment history not known Lymph-Vascular Invasion: Not identified Present Indeterminate Perineural Invasion: Not identified Present Indeterminate Pathologic Staging (pTNM) m (multiple primary tumors) r (recurrent) y (posttreatment) Primary Tumor (pT): pTX: Cannot be assessed pT0: No evidence of primary tumor pTis: High-grade dysplasia pT1: Tumor invades lamina propria, muscularis mucosae, or submucosa pT1a: Tumor invades lamina propria or muscularis mucosae pT1b: Tumor invades submucosa pT2: Tumor invades muscularis propria pT3: Tumor invades adventitia pT4: Tumor invades adjacent structures (specify): pT4a: Resectable tumor invading pleura, pericardium, or diaphragm pT4b: Unresectable tumor invading other adjacent structures, such as aorta, vertebral body, trachea, etc Regional Lymph Nodes (pN): pNX: Cannot be assessed pN0: No regional lymph node metastasis ( 0 / ) pN1: Regional lymph node metastasis involving 1 to 2 nodes ( / ) pN2: 3 to 6 nodes involved ( / ) pN3: 7 or more nodes involved ( / ) No nodes submitted or found Distant Metastasis (pM): Not applicable pM1: Distant metastasis at Additional Pathologic Findings: None identified Intestinal metaplasia (Barrett’s esophagus) Dysplasia: Low grade High grade Esophagitis (type): Gastritis (type): Other (specify): Ancillary Studies: Clinical History: Barrett’s esophagus Other (specify): Not known Comment(s):