History of Previous Tumor/Familial Syndrome:
    None known
    Known (specify, if known: ):
    Not specified

Specimen Type/Procedure:
Open biopsy
Resection
Stereotactic biopsy
Other (specify):
Not specified

Specimen Handling:
   Squash/smear/touch preparation
   Frozen section
   Tissue for electron microscopy
   Frozen tissue
   Unfrozen for routine permanent paraffin sections
   Other (specify):
   Not specified

Specimen Size:
       Greatest dimension (cm):
       Additional dimensions: cm (for fragmented tissue, an aggregate size may be given)
       Cannot be determined:

Laterality:
Right
Left
Bilateral
Not specified
Not applicable

Tumor Site:
   Skull: Specify further (eg, frontal, parietal, temporal, occipital), if known
   Dura: Specify further (eg, cerebral (convexity/lobe, falx, tentorium, sphenoid wing, skull base, other), spinal or other), if known
   Leptomeninges: Specify further (eg, cerebral (convexity/lobe), spinal, or other), if known
   Brain/cerebrum: Specify lobe(s) (eg, frontal, temporal, parietal, occipital), if known
   Basal ganglia
   Thalamus
   Hypothalamus
   Pineal
   Cerebellum
   Cerebellopontine angle
   Suprasellar
   Sella
   Other (specify, if known: )
   Cranial nerve: Specify I-XII, if known
   Ventricle: Specify lateral, third, fourth, cerebral aqueduct, if known
   Brainstem: Specify midbrain, pons, or medulla, if known
   Spine (vertebral column): Specify bony level (eg, C5, T2, L3), if known
   Spinal Cord: Specify bony level (eg, C5, T2, L3), if known; specify spinal location (eg, extradural, intradural-extramedullary, intramedullary, conus medullaris, filum terminale), if known
   Spinal nerve root(s): Specify bony level (eg, C5, T2, L3), if known; specify location (eg, intradural, foramen), if known
   Cranial or peripheral nerve: Specify site, if known
   Ganglion: Specify site, if known
   Other (specify):
   Not specified

Histologic Type and Grade (applicable World Health Organization WHO classification and grade):
   Astrocytic Tumors:
       Pilocytic astrocytoma (WHO grade I)
       Pilomyxoid astrocytoma (WHO grade II)
       Subependymal giant cell astrocytoma (WHO grade I)
       Pleomorphic xanthoastrocytoma (WHO grade II)
       Pleomorphic xanthoastrocytoma with anaplastic features (WHO grade not assigned)
       Diffuse astrocytoma (WHO grade II):
           Fibrillary astrocytoma (WHO grade II)
           Protoplasmic astrocytoma (WHO grade II)
           Gemistocytic astrocytoma (WHO grade II)
       Anaplastic astrocytoma (WHO grade III)
       Glioblastoma (WHO grade IV):
           Giant cell glioblastoma (WHO grade IV)
           Gliosarcoma (WHO grade IV)
       Gliomatosis cerebri (usually WHO grade III; diagnosis requires clinical-pathological correlation)
       Astrocytoma, not otherwise characterized (WHO grades I-IV)
   Oligodendroglial Tumors:
       Oligodendroglioma (WHO grade II)
       Anaplastic oligodendroglioma (WHO grade III)
   Oligoastrocytic Tumors (mixed glioma):
       Oligoastrocytoma (WHO grade II)
       Anaplastic oligoastrocytoma (WHO grade III)
   Ependymal Tumors:
       Subependymoma (WHO grade I)
       Myxopapillary ependymoma (WHO grade I)
       Ependymoma (WHO grade II):
           Cellular ependymoma (WHO grade II)
           Papillary ependymoma (WHO grade II)
           Clear cell ependymoma (WHO grade II)
           Tanycytic ependymoma (WHO grade II)
       Anaplastic ependymoma (WHO grade III)
   Choroid Plexus Tumors:
       Choroid plexus papilloma (WHO grade I)
       Atypical choroid plexus papilloma (WHO grade II)
       Choroid plexus carcinoma (WHO grade III)
   Other Neuroepithelial Tumors:
       Astroblastoma (WHO grade not assigned)
       Chordoid glioma of the third ventricle (WHO grade II)
       Angiocentric glioma (WHO grade I)
   Neuronal and Mixed Neuronal-Glial Tumors:
       Dysplastic gangliocytoma of cerebellum (Lhermitte-Duclos) (WHO grade I)
       Desmoplastic infantile astrocytoma/ganglioglioma (WHO grade I)
       Dysembryoplastic neuroepithelial tumor (WHO grade I)
       Gangliocytoma (WHO grade I)
       Ganglioglioma (WHO grade I)
       Anaplastic ganglioglioma (WHO grade III)
       Central neurocytoma (WHO grade II)
       Extraventricular neurocytoma (WHO grade II)
       Cerebellar liponeurocytoma (WHO grade II)
       Papillary glioneuronal tumor (PGNT) (WHO grade I)
       Rosette-forming glioneuronal tumor of the fourth ventricle (RGNT) (WHO grade I)
       Paraganglioma of the spinal cord (WHO grade I)
   Tumors of the Pineal Region:
       Pineocytoma (WHO grade I)
       Pineal parenchymal tumor of intermediate differentiation (WHO II III)
       Pineoblastoma (WHO grade IV)
       Papillary tumor of the pineal region (WHO grade II-III)
   Embryonal Tumors:
       Medulloblastoma, not otherwise characterized (WHO grade IV):
           Desmoplastic/nodular medulloblastoma (WHO grade IV)
           Medulloblastoma with extensive nodularity (WHO grade IV)
           Anaplastic medulloblastoma (WHO grade IV)
           Large cell medulloblastoma (WHO grade IV)
       Central nervous system (CNS) primitive neuroectodermal tumor (PNET) (WHO grade IV):
           Medulloepithelioma (WHO grade IV)
           Neuroblastoma (WHO grade IV)
           Ganglioneuroblastoma (WHO grade IV)
           Ependymoblastoma (WHO grade IV)
       Atypical teratoid/rhabdoid tumor (WHO grade IV)
   Tumors of Cranial and Paraspinal Nerves:
       Schwannoma (WHO grade I): :
           Cellular (WHO grade I)
           Plexiform (WHO grade I)
           Melanotic (WHO grade I)
       Neurofibroma (WHO grade I):
           Plexiform (WHO grade I)
       Perineurioma (WHO grade I):
           Intraneural perineurioma (WHO grade I)
           Soft tissue perineurioma (WHO grade I)
       Ganglioneuroma (WHO grade I)
       Malignant peripheral nerve sheath tumor (MPNST) (WHO grade II-IV):
           Epithelioid (WHO grade II-IV)
           MPNST with divergent mesenchymal and/or epithelial differentiation (WHO grade II-IV)
   Tumors of the Meninges/Meningothelial Cells:
       Meningioma (WHO grade I):
           Meningothelial (WHO grade I)
           Fibrous (fibroblastic) (WHO grade I)
           Transitional (mixed) (WHO grade I)
           Psammomatous (WHO grade I)
           Angiomatous (WHO grade I)
           Microcystic (WHO grade I)
           Secretory (WHO grade I)
           Lymphoplasmacyte-rich (lymphoplasmacytic) (WHO grade I)
           Metaplastic (WHO grade I)
       Atypical meningioma (WHO grade II)
       Clear cell meningioma (WHO grade II)
       Chordoid meningioma (WHO grade II)
       Anaplastic meningioma (WHO grade III)
       Papillary meningioma (WHO grade III)
       Rhabdoid meningioma (WHO grade III)
       Other (specify):
   Mesenchymal (Nonmeningothelial) Tumors:
       Lipoma
       Angiolipoma Hibernoma Liposarcoma (intracranial) Solitary fibrous tumor Fibrosarcoma Malignant fibrous histiocytoma Leiomyoma Leiomyosarcoma
       Rhabdomyoma Rhabdomyosarcoma Chondroma
       Chondrosarcoma
       Osteosarcoma Osteochondroma Hemangioma Epithelioid hemangioendothelioma Hemangiopericytoma Angiosarcoma Kaposi sarcoma
       Chordoma
       Mesenchymal, nonmeningothelial tumor, other (specify type, if possible):
       Sarcoma, primary CNS (specify type, if possible):
   Primary Melanotic Tumors:
       Diffuse melanocytosis
       Melanocytoma
       Malignant melanoma
       Meningeal melanomatosis
   Tumors of Uncertain Histogenesis:
       Hemangioblastoma (WHO grade I)
   Lymphoma and Hematopoietic Tumors:
       Malignant lymphoma (specify type, if possible):
       Plasmacytoma
       Granulocytic sarcoma
       Hematopoietic neoplasm, other (specify type, if possible):
   Germ Cell Tumors:
       Germinoma
       Embryonal carcinoma
       Yolk sac tumor
       Choriocarcinoma
       Teratoma, mature
       Teratoma, immature
       Teratoma with malignant transformation
       Malignant mixed germ cell tumor (specify components, eg, germinoma, embryonal, yolk sac, choriocarcinoma, teratoma):
   Tumors of the Sellar Region:
       Craniopharyngioma, adamantinomatous (WHO grade I)
       Craniopharyngioma, papillary (WHO grade I)
       Granular cell tumor (WHO grade I)
       Pituicytoma (WHO grade I)
       Spindle cell oncocytoma (WHO grade I)
       Pituitary adenoma (specify nonfunctional or hormone expression, if known):
       Pituitary carcinoma
       Pituitary hyperplasia
       Other (specify):
   Other/Nonclassifiable:
       Other(s) (specify):
       Malignant neoplasm, type cannot be determined

Histologic Grade (WHO histologic grade):
Not applicable
Cannot be determined
WHO grade I
WHO grade II
WHO grade III
WHO grade IV
WHO grade not assigned
Other (specify):

Margins (for resections of malignant peripheral nerve sheath tumors only) :
    Cannot be assessed
    Margins not involved by tumor
    Margins involved by tumor:

Ancillary Studies:
       None performed
       Immunohistochemistry (specify):
       Electron microscopy
       Molecular genetic studies (specify) ():
           1p deletion identified
           1p deletion not identified
           19q deletion identified
           19q deletion not identified
           Other (specify):
       Other (specify):

Additional Pathologic Findings:

Comment(s):