Specimen: Ampulla of Vater Other organs received: Stomach Head of pancreas Duodenum Common bile duct Gallbladder Other (specify): Not specified Procedure: Ampullectomy Pancreaticoduodenectomy (Whipple resection) Other (specify): Not specified Tumor Site: Intra-ampullary Peri-ampullary Papilla of Vater (junction of ampullary and duodenal mucosa) Other (specify): Cannot be determined Not specified Tumor Size: Greatest dimension: cm Additional dimensions: cm Cannot be determined (see Comment) Histologic Type: Adenocarcinoma (not otherwise characterized) Papillary adenocarcinoma Adenocarcinoma, intestinal type Mucinous adenocarcinoma Clear cell adenocarcinoma Signet-ring cell carcinoma Adenosquamous carcinoma Squamous cell carcinoma Small cell carcinoma Other (specify): Carcinoma, not otherwise specified Histologic Grade: Not applicable (histologic type not usually graded) GX: Cannot be assessed G1: Well differentiated G2: Moderately differentiated G3: Poorly differentiated G4: Undifferentiated Other (specify): Microscopic Tumor Extension: Cannot be assessed No evidence of primary tumor Carcinoma in situ Tumor limited to ampulla of Vater or sphincter of Oddi Tumor invades duodenal wall Tumor invades pancreas Tumor invades peripancreatic soft tissues Tumor invades extrapancreatic common bile duct Tumor invades other adjacent organs or structures other than pancreas: Margins: Ampullectomy Specimen: Cannot be assessed Margins uninvolved by invasive carcinoma, distance of invasive carcinoma from closest margin: mm at Margins involved by invasive carcinoma: Not applicable Pancreaticoduodenal Resection Specimen: Proximal Mucosal Margin (Gastric or Duodenal): Cannot be assessed Uninvolved by invasive carcinoma Involved by invasive carcinoma Intramucosal carcinoma /adenoma not identified at proximal margin Intramucosal carcinoma/adenoma present at proximal margin Distal Margin (Distal Duodenal or Jejunal): Cannot be assessed Uninvolved by invasive carcinoma Involved by invasive carcinoma Intramucosal carcinoma/adenoma not identified at distal margin Intramucosal carcinoma /adenoma present at distal margin Pancreatic Retroperitoneal (Uncinate) Margin: Not applicable Cannot be assessed Uninvolved by invasive carcinoma Involved by invasive carcinoma (tumor present 0-1 mm from margin) Bile Duct Margin: Not applicable Cannot be assessed Margin uninvolved by invasive carcinoma Margin involved by invasive carcinoma Distal Pancreatic Resection Margin: Not applicable Cannot be assessed Margin uninvolved by invasive carcinoma Margin involved by invasive carcinoma Distance of invasive carcinoma from closest margin: at Lymph-Vascular Invasion: Not identified Present Indeterminate Perineural Invasion: Not identified Present Indeterminate Pathologic Staging (pTNM) (Note F) TNM Descriptors: m (multiple primary tumors) r (recurrent) y (post-treatment) Primary Tumor (pT): pTX: Cannot be assessed pT0: No evidence of primary tumor pTis: Carcinoma in situ pT1: Tumor limited to ampulla of Vater or sphincter of Oddi pT2: Tumor invades duodenal wall pT3: Tumor invades pancreas pT4: Tumor invades peripancreatic soft tissues or other adjacent organs or structures Regional Lymph Nodes (pN): pNX: Cannot be assessed pN0: No regional lymph node metastasis ( 0 / ) pN1: Regional lymph node metastasis ( / ) No nodes submitted or found Distant Metastasis (pM): Not applicable pM1: Distant metastasis at Additional Pathologic Findings: None identified Dysplasia/adenoma Other (specify): Ancillary Studies: Clinical History: Familial adenomatous polyposis coli Other (specify): Not known Comment(s):